Alabama is the 30th largest state in the United States with 52,423 square miles (135,775 km2) of total area. 3.19% of that is water, making Alabama 23rd in the amount of surface water, also giving it the second largest inland waterway system in the United States. About three-fifths of the land area is a gentle plain with a general decline towards the Mississippi River and the Gulf of Mexico. The North Alabama region is mostly mountainous, with the Tennessee River cutting a large valley creating numerous creeks, streams, rivers, mountains, and lakes. The lowest point east of the Mississippi River lies in Dekalb County along a creek cutting tower ridges, and creating Buck's Pocket State Park. Another natural wonder is "Land Bridge", the longest natural bridge span east of the Mississippi River. Alabama generally ranges in elevation from sea level at Mobile Bay, to a little more than 1,800 feet (550 m) in the Appalachian mountains in the northeast. The highest point is Mount Cheaha.

Among Native American people once living in present Alabama were Alabama (Alibamu), Cherokee, Chickasaw, Choctaw, Creek, Koasati, and Mobile. Trade with the Northeast via the Ohio River began during the Burial Mound Period (1000 BC-A.D. 700) and continued until European contact. Meso-American influence is evident in the agrarian Mississippian culture that followed.

The French founded the first European settlement in the state with the establishment of Mobile in 1702. Southern Alabama was French from 1702 to 1763, part of British West Florida from 1763 to 1780, and part of Spanish West Florida from 1780 to 1814. Northern and central Alabama was part of British Georgia from 1763 to 1783 and part of the American Mississippi territory thereafter. Its statehood was delayed by the lack of a coastline (rectified when Andrew Jackson captured Spanish Mobile in 1814). Alabama was the twenty-second state admitted to the Union, in 1819.

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